Samuel was born 22 Mar 1864 in County Down, Ireland. He was baptised 31 Jul 1864 in Magherally Presbyterian Church, County Down, Ireland.
Samuel's parents were Robert Knox and Martha Pedan.
Samuel married Eliza Ellen Bentley 18 Jul 1888 in Lisburn, County Antrim, Ireland
Samuel died 8 Jun in 1944 in Toronto, Ontario, Canada. Samuel is buried at Mount Pleasant Cemetery, Toronto, Ontario, Canada.
Children of Samuel Prenter Knox and Eliza Ellen Bentley include:
William John Knox
Catherine Bentley Knox
Eliza Ellen Knox
Julia Astel Knox